Recombinant SARS-Cov-2 Spike RBD protein (N501Y), His (HEK293)
重组SARS冠状病毒2 Spike突变蛋白RBD(N501Y) (His Tag)
| 英文名称 | Recombinant SARS-Cov-2 Spike RBD protein (N501Y), His (HEK293) |
| 中文名称 | 重组SARS冠状病毒2 Spike突变蛋白RBD(N501Y) (His Tag) |
| 别 名 | SARS-CoV-2 spike protein; 2019-nCOV Spike protein; Spike glycoprotein; Spike protein S1; Surface glycoprotein; Spike protein RBD; SPIKE_SARS2; 2019-nCOV Spike protein(N501Y), Recombinant (His Tag); Recombinant SARS-COV-2 S protein RBD (N501Y) Protein. ;Recombinant SARS-Cov-2 Spike RBD protein (N501Y), His (HEK293) 突变型新冠蛋白; 新冠病毒S蛋白突变体（N501Y）; 重组新冠病毒 Spike突变蛋白RBD(N501Y); 新型冠状病毒Spike突变体蛋白; |
| 理论分子量 | 26.2kDa |
| 检测分子量 | 35 kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | ＞0.5 mg/ml |
| 物 种 | SARS-Cov-2 |
| 序 列 | 319-541/1273 |
| 纯 度 | >95% as determined by SDS-PAGE |
| 纯化方法 | AC |
| 内毒素 | Not analyzed |
| 表达系统 | HEK293 cell |
| 活性 | Yes |
| 标签 | His |
| 缓 冲 液 | Lyophilized from 0.22 um filtered solution in PBS (pH=7.4). Normally 5% trehalose is added as protectant before lyophilization. |
| 保存条件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 | The ongoing coronavirus disease 2019 (COVID-19) pandemic has prioritized the development of small-animal models for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The resulting mouse-adapted strain at passage 6 (called MASCp6) showed increased infectivity in mouse lung and led to interstitial pneumonia and inflammatory responses in both young and aged mice after intranasal inoculation. Deep sequencing revealed a panel of adaptive mutations potentially associated with the increased virulence. In particular, the N501Y mutation is located at the receptor binding domain (RBD) of the spike protein |
本产品仅供科研使用.请勿用于医药,不能用于临床治疗诊断使用！