重组人白介素-10 Recombinant Human IL-10

IL10 is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes。 This cytokine has pleiotropic effects in immunoregulation and inflammation。 It down-regulates the expression of Th1 cytokines，MHC class II Ags，and costimulatory molecules on macrophages。 It also enhances B cell survival，proliferation，and antibody production。 This cytokine can block NF-kappa B activity，and is involved in the regulation of the JAK-STAT signaling pathway。 Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract。

重组人白介素-10 Recombinant Human IL-10

人白介素-10重组蛋白是在大肠杆菌中重组表达的，由两条共价结合的多肽链组成；每条链包含有161个氨基酸，分子量为18606。29Da。该人白介素-10重组蛋白最终由标准的色谱技术纯化出。

重组人白介素-10 Recombinant Human IL-10