NFKB1 polyclonal antibody
产品名称： NFKB1 polyclonal antibody
英文名称： NFKB1 polyclonal antibody
产品编号： PAB24772
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of NFKB1.
- Immunogen:
- A synthetic peptide corresponding to NFKB1.
- Host:
- Rabbit
- Theoretical MW (kDa):
- 105
- Reactivity:
- Human
- Specificity:
- NFKB1 polyclonal antibody detects endogenous levels of NFKB1 protein.
- Form:
- Liquid
- Purification:
- Antigen affinity purification
- Concentration:
- 1 mg/mL
- Storage Buffer:
- In PBS, pH 7.2 (0.05% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Western Blot (1:500-1:1000)
Immunohistochemistry (1:50-1:200)
Immunoprecipitation (1:50-1:200)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Applications
- Western Blot (Cell lysate)
- Western blot analysis of HeLa cell lysate with NFKB1 polyclonal antibody (Cat # PAB24772).
- Entrez GeneID:
- 4790
- Gene Name:
- NFKB1
- Gene Alias:
- DKFZp686C01211,EBP-1,KBF1,MGC54151,NF-kappa-B,NFKB-p105,NFKB-p50,p105,p50
- Gene Description:
- nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
- Omim ID:
- 164011
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- DNA binding factor KBF1,NF-kappabeta,nuclear factor NF-kappa-B p50 subunit,nuclear factor kappa-B DNA binding subunit,nuclear factor kappa-B, subunit 1
- Interactome
- Gene Pathway
- Acute myeloid leukemia
- Adipocytokine signaling pathway
- Apoptosis
- B cell receptor signaling pathway
- Chemokine signaling pathway
- Chronic myeloid leukemia
- Epithelial cell signaling in Helicobacter pylori infection
- MAPK signaling pathway
- Metabolic pathways
- Neurotrophin signaling pathway
- Pancreatic cancer
- Pathways in cancer
- Prostate cancer
- Small cell lung cancer
- T cell receptor signaling pathway
- Toll-like receptor signaling pathway
- Related Disease
- Abortion, Spontaneous
- Acute Lung Injury
- Adenocarcinoma
- Alcoholism
- Alzheimer Disease
- Alzheimer disease
- Arthritis, Psoriatic
- Arthritis, Rheumatoid
- Asthma
- Atherosclerosis
- Atherosclerosis
- Behcet Syndrome
- Birth Weight
- Breast cancer
- Breast Neoplasms
- Calcinosis
- Carcinoid Tumor
- Carcinoma
- Carcinoma, Hepatocellular