MAPK8 monoclonal antibody, clone 279Q38
产品名称： MAPK8 monoclonal antibody, clone 279Q38
英文名称： MAPK8 monoclonal antibody, clone 279Q38
产品编号： MAB1908
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against partial recombinant MAPK8.
- Immunogen:
- Recombinant protein corresponding to human MAPK8.
- Host:
- Mouse
- Reactivity:
- Human, Mouse, Rat
- Form:
- Liquid
- Isotype:
- IgG1
- Storage Buffer:
- In PBS, pH 7.3 (1% BSA, 0.08% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
- Recommend Usage:
- Western Blot (1-5 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- JNK1 Inhibits GluR1 Expression and GluR1-Mediated Calcium Influx through Phosphorylation and Stabilization of Hes-1.
Lin CH, Lee EH.J Neurosci. 2012 Feb 1;32(5):1826-46.
- 2.
- In vivo role of p38 mitogen-activated protein kinase in mediating the anti-inflammatory effects of CpG oligodeoxynucleotide in murine asthma.
Choudhury BK, Wild JS, Alam R, Klinman DM, Boldogh I, Dharajiya N, Mileski WJ, Sur S.J Immunol. 2002 Nov 15;169(10):5955-61.
- 3.
- Involvement of the MAP kinase pathways in induction of GADD45 following UV radiation.
Tong T, Fan W, Zhao H, Jin S, Fan F, Blanck P, Alomo I, Rajasekaran B, Liu Y, Holbrook NJ, Zhan Q.Exp Cell Res. 2001 Sep 10;269(1):64-72.
- 4.
- A novel mitogen-activated protein kinase is responsive to Raf and mediates growth factor specificity.
Janulis M, Trakul N, Greene G, Schaefer EM, Lee JD, Rosner MR.Mol Cell Biol. 2001 Mar;21(6):2235-47.
- Entrez GeneID:
- 5599
- Gene Name:
- MAPK8
- Gene Alias:
- JNK,JNK1,JNK1A2,JNK21B1/2,PRKM8,SAPK1
- Gene Description:
- mitogen-activated protein kinase 8
- Omim ID:
- 601158
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq
- Other Designations:
- JNK1 alpha protein kinase,JNK1 beta protein kinase,JUN N-terminal kinase,OTTHUMP00000019552,OTTHUMP00000019555,OTTHUMP00000019556,OTTHUMP00000019558,c-Jun N-terminal kinase 1,mitogen-activated protein kinase 8 isoform JNK1 alpha1,mitogen-activated protein
- Interactome
- Gene Pathway
- Adipocytokine signaling pathway
- Colorectal cancer
- Epithelial cell signaling in Helicobacter pylori infection
- ErbB signaling pathway
- Fc epsilon RI signaling pathway
- Focal adhesion
- GnRH signaling pathway
- Insulin signaling pathway
- MAPK signaling pathway
- Neurotrophin signaling pathway
- Pancreatic cancer
- Pathways in cancer
- Toll-like receptor signaling pathway
- Type II diabetes mellitus
- Wnt signaling pathway