FITC标记的KIAA1688蛋白抗体
产品名称： FITC标记的KIAA1688蛋白抗体
英文名称： Anti-KIAA1688/FITC
产品编号： HZ-17022R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-KIAA1688/FITC Conjugated antibody
FITC标记的KIAA1688蛋白抗体
| 英文名称 | Anti-KIAA1688/FITC |
| 中文名称 | FITC标记的KIAA1688蛋白抗体 |
| 别 名 | ARHGAP39; CrGAP; RHG39_HUMAN; Uncharacterized protein KIAA1688; Vilse. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 免疫学 信号转导 G蛋白偶联受体 G蛋白信号 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Cow, Horse, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 121kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human KIAA1688 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: GTPase-activating proteins (GAPs) accelerate the intrinsic rate of GTP hydrolysis of Ras-related proteins, resulting in down regulation of their active form. KIAA1688, also known as ARHGAP39 (Rho GTPase activating protein 39), CrGAP or Vilse, is a 1,083 amino acid nuclear protein that contains one MyTH4 domain, one Rho-GAP domain and two WW domains. KIAA1688 is encoded by a gene located on human chromosome 8, which consists of nearly 146 million bases and encodes approximately 800 genes. Chromosome 8 is associated with a variety of diseases and malignancies. Schizophrenia, bipolar disorder, Trisomy 8, Pfeiffer syndrome, congenital hypothyroidism, Waardenburg syndrome and some leukemias and lymphomas are thought to occur as a result of defects in specific genes that maps to chromosome 8. Function: KIAA1688 was identified as a hypothetical protein predicted from the in silico analysis of long cDNAS isolated in the Kazusa cDNA sequencing project. The function of KIAA1688 has not been characterized. Subcellular Location: Nuclear Similarity: Contains 1 MyTH4 domain. Contains 1 Rho-GAP domain. Contains 2 WW domains. Database links: Entrez Gene: 80728 Human SwissProt: Q9C0H5 Human SwissProt: P59281 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
（GTP酶激活蛋白（间隙）accelerate固有的GTP水解率的Ras相关蛋白的调控下，resulting其主动形式。kiaa1688，也知道作为arhgap39（Rho GTP酶激活蛋白（39），crgap或vilse冰（1083个氨基酸的核蛋白，含有一myth4域，一个域的Rho GAP和两个WW域。kiaa1688冰城A基因编码的并置在人类染色体8，这部由近146万基地和encodes约800个基因。染色体8和一个冰的相关规定和malignancies品种。schizophrenia，双相情感障碍，trisomy 8 Pfeiffer综合征，先天性hypothyroidism Waardenburg综合征，和一些leukemias和lymphomas是两个occur思想作为一个结果的特异性基因缺陷，染色体上的两个8。