CILP monoclonal antibody (M01), clone 2C5
产品名称: CILP monoclonal antibody (M01), clone 2C5
英文名称: CILP monoclonal antibody (M01), clone 2C5
产品编号: H00008483-M01
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against a partial recombinant CILP.
- Immunogen:
- CILP (NP_003604, 129 a.a. ~ 226 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Sequence:
- NCSNYTVRFLCPPGSLRRDTERIWSPWSPWSKCSAACGQTGVQTRTRICLAEMVSLCSEASEEGQHCMGQDCTACDLTCPMGQVNADCDACMCQDFML
- Host:
- Mouse
- Reactivity:
- Human
- Isotype:
- IgG1 Kappa
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
- MSDS:
- Download
- Applications
- Sandwich ELISA (Recombinant protein)
- Detection limit for recombinant GST tagged CILP is approximately 0.1ng/ml as a capture antibody.
- Protocol Download
- Entrez GeneID:
- 8483
- GeneBank Accession#:
- NM_003613
- Protein Accession#:
- NP_003604
- Gene Name:
- CILP
- Gene Alias:
- CILP-1,HsT18872
- Gene Description:
- cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Major alterations in the composition of the cartilage extracellular matrix occur in joint disease, such as osteoarthrosis. This gene encodes the cartilage intermediate layer protein (CILP), which increases in early osteoarthrosis cartilage. The encoded protein was thought to encode a protein precursor for 2 different proteins, namely CILP and a homolog of NTPPHase, however later studies identified no nucleotide pyrophosphatase phosphodiesterase (NPP) activity. One isoform of the protein, CILP-1, functions as an IGF-1 antagonist. [provided by RefSeq
- Other Designations:
- cartilage intermediate layer protein,cartilage intermediate layer protein 1 C1,cartilage intermediate layer protein 1 C2
- Related Disease