FITC标记的肿瘤坏死因子受体相互作用蛋白抗体
产品名称: FITC标记的肿瘤坏死因子受体相互作用蛋白抗体
英文名称: Anti-TRIP/FITC
产品编号: HZ-4983R-FITC
产品价格: null
产品产地: 中国/上海
品牌商标: HZbscience
更新时间: 2023-08-17T10:24:20
使用范围: ICC=1:50-200 IF=1:50-200
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Rabbit Anti-TRIP/FITC Conjugated antibody
FITC标记的肿瘤坏死因子受体相互作用蛋白抗体
英文名称 | Anti-TRIP/FITC |
中文名称 | FITC标记的肿瘤坏死因子受体相互作用蛋白抗体 |
别 名 | RING finger protein 206; RNF206; TRAF Interacting Protein; TRAIP; TRIP. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 肿瘤 转录调节因子 细胞膜受体 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | |
产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 53kDa |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human TRIP |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: RING finger motif and a putative coiled-coil domain. A similar murine protein interacts with TNFR-associated factor 1 (TRAF1), TNFR-associated factor 2 (TRAF2), and cylindromatosis. The interaction with TRAF2 inhibits TRAF2-mediated nuclear factor kappa-B, subunit 1 activation that is required for cell activation and protection against apoptosis. Function: Inhibits activation of NF-kappa-B mediated by TNF. Subunit: Binds TRAF1 and TRAF2 and is part of the receptor-TRAF signaling complex. Interacts with CYLD. Subcellular Location: Cytoplasm. Cytoplasm, perinuclear region. Similarity: Contains 1 RING-type zinc finger. Database links: Entrez Gene: 10293 Human Omim: 605958 Human SwissProt: Q9BWF2 Human Unigene: 517972 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
环指基序和一个假定的卷曲螺旋结构域。类似的鼠蛋白与TNFR相关因子1(TRAF1)、TNFR相关因子2(TRAF2)和圆柱瘤病相互作用。与TRAF2的相互作用抑制TRAF2介导的核因子-κB亚单位1,活化是细胞的活化和对细胞凋亡的保护要求。