COL7A1 polyclonal antibody
产品名称： COL7A1 polyclonal antibody
英文名称： COL7A1 polyclonal antibody
产品编号： PAB7538
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Goat polyclonal antibody raised against synthetic peptide of COL7A1.
- Immunogen:
- A synthetic peptide corresponding to human COL7A1.
- Sequence:
- C-TVQYSDDPRTEF
- Host:
- Goat
- Theoretical MW (kDa):
- 295
- Reactivity:
- Rat
- Specificity:
- This product does not work on cryostat sections of normal human Skin.
- Form:
- Liquid
- Purification:
- Antigen affinity purification
- Concentration:
- 0.5 mg/mL
- Storage Buffer:
- In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- ELISA (1:32000)
Western Blot (0.1-1.5 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Type VII collagen is required for Ras-driven human epidermal tumorigenesis.
Ortiz-Urda S, Garcia J, Green CL, Chen L, Lin Q, Veitch DP, Sakai LY, Lee H, Marinkovich MP, Khavari PA.Science. 2005 Mar 18;307(5716):1773-6.
- Entrez GeneID:
- 1294
- Protein Accession#:
- NP_000085.1
- Gene Name:
- COL7A1
- Gene Alias:
- EBD1,EBDCT,EBR1
- Gene Description:
- collagen, type VII, alpha 1
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes the alpha chain of type VII collagen. The type VII collagen fibril, composed of three identical alpha collagen chains, is restricted to the basement zone beneath stratified squamous epithelia. It functions as an anchoring fibril between the external epithelia and the underlying stroma. Mutations in this gene are associated with all forms of dystrophic epidermolysis bullosa. In the absence of mutations, however, an acquired form of this disease can result from an autoimmune response made to type VII collagen. [provided by RefSeq
- Other Designations:
- LC collagen,alpha 1 type VII collagen,collagen VII, alpha-1 polypeptide,long chain collagen