FITC标记的溶质载体家族蛋白34成员A3抗体
产品名称: FITC标记的溶质载体家族蛋白34成员A3抗体
英文名称: Anti-SLC34A3/FITC
产品编号: HZ-20801R-FITC
产品价格: null
产品产地: 中国/上海
品牌商标: HZbscience
更新时间: 2023-08-17T10:24:20
使用范围: ICC=1:50-200 IF=1:50-200
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Rabbit Anti-SLC34A3/FITC Conjugated antibody
FITC标记的溶质载体家族蛋白34成员A3抗体
英文名称 | Anti-SLC34A3/FITC |
中文名称 | FITC标记的溶质载体家族蛋白34成员A3抗体 |
别 名 | HHRH; Na(+) dependent phosphate cotransporter 2C; Na(+) Pi cotransporter 2C; Na(+)-dependent phosphate cotransporter 2C; Na(+)/Pi cotransporter 2C; NaPi 2c; NaPi-2c; NPT2C; NPT2C_HUMAN; NPTIIC; SLC34A3; Sodium dependent phosphate transport protein 2C; Sodium inorganic phosphate cotransporter IIC; Sodium phosphate cotransporter 2C; Sodium phosphate transport protein 2C; Sodium-dependent phosphate transport protein 2C; Sodium-phosphate transport protein 2C; Sodium/inorganic phosphate cotransporter IIC; Sodium/inorganic phosphate cotransporter, type IIC; Sodium/phosphate cotransporter 2C; solute carrier family 34 (sodium phosphate) member 3; solute carrier family 34 (sodium/phosphate contransporter), member 3; solute carrier family 34 (type II sodium/phosphate contransporter), member 3; Solute carrier family 34 member 3; type IIc Na+ Pi cotransporter. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 肿瘤 细胞生物 信号转导 转运蛋白 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | |
产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 63kDa |
性 状 | Lyophilized or Liquid |
浓 度 | 2mg/1ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human SLC34A3 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: This gene encodes a member of SLC34A transporter family of proteins, and is expressed primarily in the kidney. It is involved in transporting phosphate into cells via sodium cotransport in the renal brush border membrane, and contributes to the maintenance of inorganic phosphate concentration in the kidney. Mutations in this gene are associated with hereditary hypophosphatemic rickets with hypercalciuria. Alternatively spliced transcript variants varying in the 5' UTR have been found for this gene.[provided by RefSeq, Apr 2010] Function: May be involved in actively transporting phosphate into cells via Na(+) cotransport in the renal brush border membrane. Probably mediates 20-30% of the apical influx. Subcellular Location: Membrane. DISEASE: Hereditary hypophosphatemic rickets with hypercalciuria. Similarity: Belongs to the SLC34A transporter family. Database links: Entrez Gene: 142680 Human Entrez Gene: 142681 Mouse Entrez Gene: 246234 Rat Omim: 609826 Human SwissProt: Q8N130 Human SwissProt: Q80SU6 Mouse SwissProt: Q8K4R8 Rat Unigene: 432442 Human Unigene: 346652 Mouse Unigene: 490356 Mouse Unigene: 15318 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
该基因编码SLC34A转运蛋白家族成员,主要表达于肾脏。它参与通过钠在肾刷状边界膜中的共转运将磷酸盐转运到细胞中,并有助于维持肾脏中的无机磷酸盐浓度。该基因的突变与遗传性低磷佝偻病伴高钙尿症有关。此外,还发现了该基因的5’UTR中变化的剪接转录体变体。