FITC标记的骨形态发生蛋白7抗体
产品名称： FITC标记的骨形态发生蛋白7抗体
英文名称： Anti-BMP7/FITC
产品编号： HZ-2242R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
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Rabbit Anti-BMP7/FITC Conjugated antibody
FITC标记的骨形态发生蛋白7抗体
| 英文名称 | Anti-BMP7/FITC |
| 中文名称 | FITC标记的骨形态发生蛋白7抗体 |
| 别 名 | bone morphogenetic protein 7 precursor; osteogenic protein 1; BMP-7; OP-1; BMP 7; Bone morphogenic protein 7; Eptotermin alfa; OP 1; OP1; BMP7_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 细胞生物 免疫学 细胞凋亡 生长因子和激素 转录调节因子 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 15.7/47kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human BMP7 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development and possible bone inductive activity. [provided by RefSeq]. Function: Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis. Subunit: Homodimer; disulfide-linked. Interacts with SOSTDC1. Interacts with TWSG1. Subcellular Location: Secreted. Tissue Specificity: Expressed in the kidney and bladder. Lower levels seen in the brain. Post-translational modifications: Several N-termini starting at positions 293, 300, 315 and 316 have been identified by direct sequencing resulting in secretion of different mature forms (PubMed:17977014). Similarity: Belongs to the TGF-beta family. Database links: Entrez Gene: 477270 Dog Entrez Gene: 655 Human Entrez Gene: 12162 Mouse Entrez Gene: 492315 Pig Entrez Gene: 85272 Rat Omim: 112267 Human SwissProt: P18075 Human SwissProt: P23359 Mouse Unigene: 473163 Human Unigene: 595 Mouse Unigene: 18030 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 骨形态发生蛋白7（BMP-7）是转化生长因子β超家族成员,参与器官发生,细胞增殖、分化及凋亡等 |
骨形态发生蛋白（BMPs）是一类分泌信号分子，可诱发异位骨的生长。许多骨形态发生蛋白是转化生长因子β（TGFB）超家族的一部分。BMP最初是通过脱钙骨提取物在骨外部位在体内诱导软骨内成骨的能力来鉴定的。根据其在胚胎发生早期的表达，该基因编码的BMP在早期发育和可能的骨诱导活性方面具有潜在的作用。[由RefSeq提供]。