FMR1 polyclonal antibody
产品名称： FMR1 polyclonal antibody
英文名称： FMR1 polyclonal antibody
产品编号： PAB14144
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Goat polyclonal antibody raised against synthetic peptide of FMR1.
- Immunogen:
- A synthetic peptide corresponding to amino acids 116-130 of human FMR1.
- Sequence:
- C-NPNKPATKDTFHKIK
- Host:
- Goat
- Theoretical MW (kDa):
- 71.2
- Reactivity:
- Human
- Specificity:
- Approx 70 Da band observed in lysates of cell lines HeLa and Jurkat (calculated MW of 71.2 KDa according to NP_002015.1).
- Form:
- Liquid
- Purification:
- Antigen affinity purification
- Concentration:
- 0.5 mg/mL
- Storage Buffer:
- In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:32000)
Western Blot (0.3-1 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Correction of fragile X syndrome in mice.
Dolen G, Osterweil E, Rao BS, Smith GB, Auerbach BD, Chattarji S, Bear MF.Neuron. 2007 Dec 20;56(6):955-62.
- Applications
- Western Blot (Cell lysate)
- FMR1 polyclonal antibody (Cat # PAB14144) (0.3 ug/mL) staining of HeLa lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
- Entrez GeneID:
- 2332
- Protein Accession#:
- NP_002015.1
- Gene Name:
- FMR1
- Gene Alias:
- FMRP,FRAXA,MGC87458,POF,POF1
- Gene Description:
- fragile X mental retardation 1
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). [provided by RefSeq
- Other Designations:
- OTTHUMP00000024197,premature ovarian failure 1
- Related Disease
- Ataxia
- Ataxia Telangiectasia
- Ataxia telangiectasia
- Attention
- Attention Deficit Disorder with Hyperactivity
- Autistic Disorder
- Cerebellar Ataxia
- Cognition
- Cognition Disorders
- Dementia
- Disease Progression
- Essential Tremor
- Essential tremor
- Fetal Diseases
- Fragile X Syndrome
- Fragile X syndrome
- Genetic Predisposition to Disease
- Genomic Instability
- Hallucinations