SPAG9 polyclonal antibody
产品名称： SPAG9 polyclonal antibody
英文名称： SPAG9 polyclonal antibody
产品编号： PAB2862
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of SPAG9.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to internal region of human SPAG9.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Ammonium sulfate precipitation
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:50-100)
Immunohistochemistry (1:10-50)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Immunogenicity study of recombinant human sperm-associated antigen 9 in bonnet macaque (Macaca radiata).
Rana R, Jagadish N, Garg M, Mishra D, Dahiya N, Chaurasiya D, Suri A.Hum Reprod. 2006 Nov;21(11):2894-900. Epub 2006 Sep 7.
- 2.
- Small interference RNA-mediated knockdown of sperm associated antigen 9 having structural homology with c-Jun N-terminal kinase-interacting protein.
Rana R, Jagadish N, Garg M, Mishra D, Dahiya N, Chaurasiya D, Suri A.Biochem Biophys Res Commun. 2006 Feb 3;340(1):158-64. Epub 2005 Dec 9.
- 3.
- Sperm associated antigen 9 (SPAG9): a new member of c-Jun NH2 -terminal kinase (JNK) interacting protein exclusively expressed in testis.
Jagadish N, Rana R, Mishra D, Kumar M, Suri A.Keio J Med. 2005 Jun;54(2):66-71.
- Applications
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Formalin-fixed and paraffin-embedded human testisreacted with SPAG9 polyclonal antibody (Cat # PAB2862), which was peroxidase-conjugated to the secondary antibody, followed by AEC staining.
This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
- Application Image
- Western Blot
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- enlarge
- ELISA
- Entrez GeneID:
- 9043
- Protein Accession#:
- NP_003962;O60271
- Gene Name:
- SPAG9
- Gene Alias:
- FLJ13450,FLJ14006,FLJ26141,FLJ34602,HLC4,JLP,KIAA0516,MGC117291,MGC14967,MGC74461,PHET,PIG6
- Gene Description:
- sperm associated antigen 9
- Omim ID:
- 605430
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Extracellular signals are transduced into cells through mitogen-activated protein kinases. The structural organization of these kinases into specific signaling domains is facilitated by scaffolding proteins involved in closely tethering different kinases so that successive phosphorylation events can occur. The protein encoded by this gene is a scaffolding protein that brings together mitogen-activated protein kinases and their transcription factor targets for the activation of specific signaling pathways. This gene which is abundantly expressed in testicular haploid germ cells encodes a protein that is recognized by sperm-agglutinating antibodies and implicated in infertility. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- HLC-4 protein,JNK interacting protein,JNK-associated leucine-zipper protein,JNK/SAPK-associated protein,Max-binding protein,c-Jun NH2-terminal kinase-associated leucine zipper protein,lung cancer oncogene 4,proliferation-inducing gene 6,sperm specific pro