DSCR1 purified MaxPab mouse polyclonal antibody (B01P)
产品名称： DSCR1 purified MaxPab mouse polyclonal antibody (B01P)
英文名称： DSCR1 purified MaxPab mouse polyclonal antibody (B01P)
产品编号： H00001827-B01P
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse polyclonal antibody raised against a full-length human DSCR1 protein.
- Immunogen:
- DSCR1 (NP_981962.1, 1 a.a. ~ 117 a.a) full-length human protein.
- Sequence:
- MKLYFAQTLHIGSSHLAPPNPDKQFLISPPASPPVGWKQVEDATPVINYDLLYAISKLGPGEKYELHAATDTTPSVVVHVCESDQEKEEEEEMERMRRPKPKIIQTRRPEYTPIHLS
- Host:
- Mouse
- Reactivity:
- Human
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody reactive against mammalian transfected lysate.
- MSDS:
Download
- Applications
- Western Blot (Transfected lysate)
- Western Blot analysis of RCAN1 expression in transfected 293T cell line (H00001827-T01) by RCAN1 MaxPab polyclonal antibody.
Lane 1: DSCR1 transfected lysate(12.87 KDa).
Lane 2: Non-transfected lysate. - Protocol Download
- Immunofluorescence
enlarge this image- Immunofluorescence of purified MaxPab antibody to DSCR1 on HeLa cell. [antibody concentration 10 ug/ml]
- Protocol Download
- Entrez GeneID:
- 1827
- GeneBank Accession#:
- NM_203417.1
- Protein Accession#:
- NP_981962.1
- Gene Name:
- RCAN1
- Gene Alias:
- ADAPT78,CSP1,DSC1,DSCR1,MCIP1,RCN1
- Gene Description:
- regulator of calcineurin 1
- Omim ID:
- 602917
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Three transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- Down syndrome candidate region 1,Down syndrome critical region gene 1,calcipressin 1,calcium and oxidant-inducible mRNA,modulatory calcineurin-interacting protein 1,myocyte-enriched calcineurin-interacting protein 1,near DSCR proline-rich protein
- Related Disease