TRADD (Human) Recombinant Protein (P01)
产品名称: TRADD (Human) Recombinant Protein (P01)
英文名称: TRADD (Human) Recombinant Protein (P01)
产品编号: H00008717-P01
产品价格: 0
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围: null
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Human TRADD full-length ORF ( NP_003780.1, 1 a.a. - 312 a.a.) recombinant protein with GST-tag at N-terminal.
- Sequence:
- MAAGQNGHEEWVGSAYLFVESSLDKVVLSDAYAHPQQKVAVYRALQAALAESGGSPDVLQMLKIHRSDPQLIVQLRFCGRQPCGRFLRAYREGALRAALQRSLAAALAQHSVPLQLELRAGAERLDALLADEERCLSCILAQQPDRLRDEELAELEDALRNLKCGSGARGGDGEVASAPLQPPVPSLSEVKPPPPPPPAQTFLFQGQPVVNRPLSLKDQQTFARSVGLKWRKVGRSLQRGCRALRDPALDSLAYEYEREGLYEQAFQLLRRFVQAEGRRATLQRLVEALEENELTSLAEDLLGLTDPNGGLA
- Theoretical MW (kDa):
- 60.6
- Preparation Method:
- in vitro wheat germ expression system
- Purification:
- Glutathione Sepharose 4 Fast Flow
- Storage Buffer:
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
- Storage Instruction:
- Store at -80°C. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- 12.5% SDS-PAGE Stained with Coomassie Blue.
- Note:
- Best use within three months from the date of receipt of this protein.
- MSDS:
- Download
- Application Image
- Enzyme-linked Immunoabsorbent Assay
- Western Blot (Recombinant protein)
- Antibody Production
- Protein Array
- Entrez GeneID:
- 8717
- GeneBank Accession#:
- NM_003789.2
- Protein Accession#:
- NP_003780.1
- Gene Name:
- TRADD
- Gene Alias:
- Hs.89862,MGC11078
- Gene Description:
- TNFRSF1A-associated via death domain
- Omim ID:
- 603500
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway. [provided by RefSeq
- Other Designations:
- TNFR1-associated death domain protein,tumor necrosis factor receptor type 1 associated death domain protein,tumor necrosis factor receptor-1-associated protein
- Gene Pathway
- Related Disease
- Ductus Arteriosus, Patent
- Genetic Predisposition to Disease
- Hematologic Diseases
- Hodgkin Disease
- Infant, Premature, Diseases
- Lupus Erythematosus, Systemic
- Lymphoma, Non-Hodgkin
- Lymphoproliferative Disorders
- Multiple Myeloma
- Occupational Diseases
- Spondylitis, Ankylosing
- Waldenstrom Macroglobulinemia
- Werner syndrome