FITC标记的NIPAL2蛋白抗体
产品名称: FITC标记的NIPAL2蛋白抗体
英文名称: Anti-NIPAL2/FITC
产品编号: HZ-11096R-FITC
产品价格: null
产品产地: 中国/上海
品牌商标: HZbscience
更新时间: 2023-08-17T10:24:20
使用范围: ICC=1:50-200 IF=1:50-200
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Rabbit Anti-NIPAL2/FITC Conjugated antibody
FITC标记的NIPAL2蛋白抗体
产品编号 | bs-11096R-FITC |
英文名称 | Anti-NIPAL2/FITC |
中文名称 | FITC标记的NIPAL2蛋白抗体 |
别 名 | NIPA like domain containing 2; NIPAL2; NPAL2; NPAL2_HUMAN. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 肿瘤 神经生物学 通道蛋白 细胞粘附分子 细胞膜蛋白 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, |
产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 41kDa |
细胞定位 | 细胞膜 |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human NIPAL2 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: Non-imprinted in Prader-Willi/Angelman syndrome (NIPA) proteins are highly conserved receptors or transporters. A family known as the NIPA-like domain containing (NPAL) proteins are closely related to the NIPA proteins, but most are uncharacterized and their functions are unknown. NPAL2 (NIPA-like domain containing 2), also known as NIPAL2, is a 368 amino acid multi-pass membrane protein belonging to the NIPA family and is encoded by a gene located on human chromosome 8. Human chromosome 8 consists of nearly 146 million base pairs, houses more than 800 genes and is associated with a variety of diseases and malignancies. Schizophrenia, bipolar disorder, Trisomy 8, Pfeiffer syndrome, congenital hypothyroidism, Waardenburg syndrome and some leukemias and lymphomas are thought to occur as a result of defects in specific genes that map to chromosome 8. Function: NPAL2 is a multi-pass membrane protein and it belongs to the NIPA family. The exact function of NPAL2 remains unknown. Subcellular Location: Membrane; Multi-pass membrane protein Similarity: Belongs to the NIPA family. Database links: UniProtKB/Swiss-Prot: Q9H841.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
Prer-Weli/Agalman综合征(NIPA)蛋白中的非印迹是高度保守的受体或转运蛋白。一个被称为NIPA样结构域的包含(NPAL)蛋白的家族与NIPA蛋白密切相关,但大多数是未鉴定的,它们的功能是未知的。NPAL2(NIPA样结构域包含2),也称为NIPAL2,是属于NIPA家族的368氨基酸多通道膜蛋白,由位于人类染色体8上的基因编码。人类8号染色体由近1亿4600万个碱基对组成,拥有800多个基因,并与多种疾病和恶性肿瘤相关。精神分裂症、双相情感障碍、8三体综合征、菲佛综合征、先天性甲状腺功能减退症、Waord-Burg综合征和一些白血病和淋巴瘤被认为是由于8号染色体的特定基因缺陷所致。