Defensin beta 1,防御素β1/Defensin β1抗体

产品编号HZ-1163R
英文名称Defensin beta 1
中文名称防御素β1/Defensin β1抗体
别 名BD 1; BD-1; BD1; beta 1; Beta defensin 1; Beta-defensin 1; DEFB 1; DEFB1; DEFB1_HUMAN; DEFB101; Defensin; Defensin beta 1 preproprotein; HBD 1; hBD-1; HBD1; MGC51822.
说 明 书0.1ml 0.2ml
研究领域细胞生物
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Mouse, Rat,
Defensin beta 1,防御素β1/Defensin β1抗体产品应用ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量4.1/8kDa
细胞定位分泌型蛋白
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from rat Defensin Beta 1
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Defensin beta 1,防御素β1/Defensin β1抗体PubMedPubMed
产品介绍background:
Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 1, an antimicrobial peptide implicated in the resistance of epithelial surfaces to microbial colonization. This gene maps in close proximity to defensin family member, defensin, alpha 1 and has been implicated in the pathogenesis of cystic fibrosis. The mature form of Beta defensin 1 is 36 amino acids.

Function:
Has bactericidal activity.

Subcellular Location:
Secreted.

Tissue Specificity:
Plasma.

Similarity:
Belongs to the beta-defensin family.

Gene ID:
64389

Database links:
Entrez Gene: 1672 Human
Entrez Gene: 64389 Rat
Omim: 602056 Human
SwissProt: P60022 Human
Unigene: 32949 Human

Defensin beta 1,防御素β1/Defensin β1抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

防御素在动物体中广泛分布的，目前已知的α－防御素有6种，研究人员从动物体的肾脏、气管、鼻粘膜与唾液中也发现了两种β防御素，在许多器官的上皮细胞与非上皮组织的细胞中发现了β－防御素。防御素的表达与病原体的入侵是紧密相关。