钙调磷酸酶A/钙依赖磷酸酶A抗体-抗体相关-抗体-生物在线
北京索莱宝科技有限公司
钙调磷酸酶A/钙依赖磷酸酶A抗体

钙调磷酸酶A/钙依赖磷酸酶A抗体

商家询价

产品名称: 钙调磷酸酶A/钙依赖磷酸酶A抗体

英文名称: PPP3CA

产品编号: bs-0030M

产品价格: null

产品产地: 北京

品牌商标: 博奥森

更新时间: 2024-12-26T14:00:32

使用范围: WB=1:100-500,ELISA=1:500-1000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,

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Calcineurin, a major soluble calmodulin binding protein in the brain, a Ca2+/calmodulin dependent serine/threonine protein phosphatase, with a relatively narrow substrate specificity. This metalloenzyme, also known as phosphatase 2B, is a heterodimer composed of a calmodulin binding, catalytic alpha subunit 61 kDa, calcineurin A) and calcium binding beta subunit (18 kDa, calcineurin B). The Ca2+ binding subunit, calcineurin B, is immunologically conserved from yeast to mammals. The presence of 2 different calcineurin B isoforms (beta 1 and beta 2) has been reported in rat testis. The catalytic subunit of calcineurin, calcineurin A, isolated from different tissues or different organisms, exhibits some immunological heterogeneity. Further, there are at least 2 isoforms of calcineurin A in bovine brain (alpha 1 and alpha 2, 61 and 59 kDa, respectively).