PIP5K1C polyclonal antibody
产品名称： PIP5K1C polyclonal antibody
英文名称： PIP5K1C polyclonal antibody
产品编号： PAB2132
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
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- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of PIP5K1C.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human PIP5K1C.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Protein G purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:100-500)
Immunohistochemistry (1:50-100)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Type I gamma phosphatidylinositol phosphate kinase targets and regulates focal adhesions.
Ling K, Doughman RL, Firestone AJ, Bunce MW, Anderson RA.Nature. 2002 Nov 7;420(6911):89-93.
- 2.
- Recruitment and regulation of phosphatidylinositol phosphate kinase type 1 gamma by the FERM domain of talin.
Di Paolo G, Pellegrini L, Letinic K, Cestra G, Zoncu R, Voronov S, Chang S, Guo J, Wenk MR, De Camilli P.Nature. 2002 Nov 7;420(6911):85-9.
- 3.
- Type I phosphatidylinositol-4-phosphate 5-kinases. Cloning of the third isoform and deletion/substitution analysis of members of this novel lipid kinase family.
Ishihara H, Shibasaki Y, Kizuki N, Wada T, Yazaki Y, Asano T, Oka Y.J Biol Chem. 1998 Apr 10;273(15):8741-8.
- Applications
- Western Blot (Cell lysate)
- The PIP5K1C polyclonal antibody (Cat # PAB2132) is used in Western blot to detect PIP5K1C in 293 cell lysate.
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Formalin-fixed and paraffin-embedded human hepatocellular carcinoma tissue reacted with PIP5K1C polyclonal antibody (Cat # PAB2132) , which was peroxidase-conjugated to the secondary antibody, followed by AEC staining.
This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. HC = hepatocarcinoma.
- Entrez GeneID:
- 23396
- Protein Accession#:
- NP_036530;O60331
- Gene Name:
- PIP5K1C
- Gene Alias:
- KIAA0589,LCCS3,PIP5K-GAMMA,PIP5Kgamma
- Gene Description:
- phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a member of the type I phosphatidylinositol-4-phosphate 5-kinase family of enzymes. A similar protein in mice is found in synapses and focal adhesion plaques, and binds the FERM domain of talin through its C-terminus. [provided by RefSeq
- Other Designations:
- Human homolog of mouse phosphatidylinositol-4-phosphate 5-kinase I-gamma,PtdIns(4)P-5-kinase,diphosphoinositide kinase,phosphatidylinositol-4-phosphate 5-kinase I-gamma,type I PIP kinase
- Related Disease