DAP5,死亡相关蛋白5抗体

产品编号HZ-1350R
英文名称DAP5
中文名称死亡相关蛋白5抗体
别 名DAP-5; DAP 5; Death Associated Protein-5; Death associated protein 5; Death-associated protein 5; eIF-4-gamma 2; eIF-4G 2; eIF4G 2; EIF4G2; Eukaryotic translation initiation factor 4 gamma 2; Nat1; Novel APOBEC-1 target 1; Translation repressor NAT1; IF4G2_HUMAN; p97.
说 明 书0.1ml 0.2ml
研究领域细胞生物 染色质和核信号 细胞凋亡
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, Guinea Pig,
DAP5,死亡相关蛋白5抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量102kDa
细胞定位细胞浆
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human DAP-5
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
DAP5,死亡相关蛋白5抗体PubMedPubMed
产品介绍background:
Death Associated Protein 5 (DAP5) is a 97 kDa protein with high amino acid sequence homology to Eukaryotic Translation Initiation Factor 4G (eIF4G). Compared with eIF4G, DAP5 lacks the N-terminal region necessary for cap-dependent translation and has a unique C-terminal part functioning as a regulator for interferon-gamma induced cell death. During apoptosis, DAP5 is cleaved at Asp790. The C-terminal truncated form of DAP5 functions as a cap-independent translation initiation factor responsible for the mediation of its own translation during apoptosis.

Subcellular Location:
Cytoplasm.

Tissue Specificity:
Ubiquitous.

Gene ID:
1982

Database links:
Entrez Gene: 1982 Human
Entrez Gene: 13690 Mouse
Entrez Gene: 361628 Rat
Omim: 602325 Human
SwissProt: P78344 Human
SwissProt: Q62448 Mouse
Unigene: 183684 Human
Unigene: 185453 Mouse
Unigene: 103276 Rat

DAP5,死亡相关蛋白5抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

DAP-5又称p97, 是白细胞转移抑制因子4G (ELF4G)家族成员. DAP-5在各种种系表达广泛并高度保守。