REN monoclonal antibody, clone 257/A5 GC10 AH4
产品名称: REN monoclonal antibody, clone 257/A5 GC10 AH4
英文名称: REN monoclonal antibody, clone 257/A5 GC10 AH4
产品编号: MAB3696
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against recombinant REN.
- Immunogen:
- Recombinant protein corresponding to human REN.
- Host:
- Mouse
- Reactivity:
- Human
- Specificity:
- This antibody recognizes prorenin and active renin.
- Form:
- Liquid
- Isotype:
- IgG1, kappa
- Storage Buffer:
- In BBS
- Storage Instruction:
- Store at 4°C.
- Recommend Usage:
- The optimal working dilution should be determined by the end user.
- Application Image
- ELISA
- Entrez GeneID:
- 5972
- Gene Name:
- REN
- Gene Alias:
- FLJ10761
- Gene Description:
- renin
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Renin catalyzes the first step in the activation pathway of angiotensinogen--a cascade that can result in aldosterone release,vasoconstriction, and increase in blood pressure. Renin, an aspartyl protease, cleaves angiotensinogen to form angiotensin I, which is converted to angiotensin II by angiotensin I converting enzyme, an important regulator of blood pressure and electrolyte balance. Transcript variants that encode different protein isoforms and that arise from alternative splicing and the use of alternative promoters have been described, but their full-length nature has not been determined. Mutations in this gene have been shown to cause familial hyperproreninemia. [provided by RefSeq
- Other Designations:
- OTTHUMP00000034311,angiotensin-forming enzyme,angiotensinogenase,renin precursor, renal
- Gene Pathway
- Related Disease
- Alzheimer Disease
- Alzheimer disease
- Arrhythmias, Cardiac
- Brain Ischemia
- Cardiovascular Diseases
- Carotid Stenosis
- Cerebrovascular Accident
- Chorioamnionitis
- Coronary Artery Disease
- Death, Sudden, Cardiac
- Diabetes Complications
- Diabetes Mellitus
- Diabetes Mellitus, Type 2
- Diabetic Angiopathies
- Diabetic Nephropathies
- Edema
- Emergencies
- Fetal Membranes, Premature Rupture
- Genetic Predisposition to Disease