FITC标记的Bcl2相互作用蛋白1抗体（转化相关基因8蛋白）
产品名称： FITC标记的Bcl2相互作用蛋白1抗体（转化相关基因8蛋白）
英文名称： Anti-BNIP1/FITC
产品编号： HZ-6681R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
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Rabbit Anti-BNIP1/FITC Conjugated antibody
FITC标记的Bcl2相互作用蛋白1抗体（转化相关基因8蛋白）
| 英文名称 | Anti-BNIP1/FITC |
| 中文名称 | FITC标记的Bcl2相互作用蛋白1抗体（转化相关基因8蛋白） |
| 别 名 | NIP1; BCL2 adenovirus E1B 19kD interacting protein 1; BCL2/adenovirus E1B 19 kDa protein-interacting protein 1; BNIP1; sec20; SEC20_HUMAN; SEC20L; Transformation-related gene 8 protein; TRG-8; TRG8; Vesicle transport protein SEC20. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 神经生物学 信号转导 细胞凋亡 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 26kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human BNIP1/TRG8 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: SNARE that may be involved in targeting and fusion of Golgi-derived retrograde transport vesicles with the ER. Required for maintenance of ER network. Implicated in the suppression of cell death. Tissue specificity: Isoform 1 is highly expressed in heart, brain, liver skeletal muscle and pancreas. Isoform 3 is moderately expressed in placenta, lung and kidney. Isoform 4 is highly expressed in testis and small intestine. Function: SNARE that may be involved in targeting and fusion of Golgi-derived retrograde transport vesicles with the ER. Required for maintenance of ER network. Implicated in the suppression of cell death. May be involved in mitochondrial autophagy. Subunit: Component of a SNARE complex consisting of STX18, USE1L, BNIP1/SEC20L and SEC22B. Interacts directly with STX18, RINT1/TIP20L and NAPA. Interacts with ZW10 through RINT1. Interacts with BCL2 and adenovirus E1B 19 kDa protein. Subcellular Location: Mitochondrion. Endoplasmic reticulum membrane; Single-pass type IV membrane protein. Tissue Specificity: Isoform 1 is highly expressed in heart, brain, liver skeletal muscle and pancreas. Isoform 3 is moderately expressed in placenta, lung and kidney. Isoform 4 is highly expressed in testis and small intestine. Post-translational modifications: 'Lys-63'-linked polyubiquitination by RNF185 allows recruiting of autophagy receptor SQSTM1, which simultaneously binds both ubiquitin and LC3 to link ubiquitination and autophagy. Similarity: Belongs to the SEC20 family. Database links: Entrez Gene: 662 Human Entrez Gene: 224630 Mouse Entrez Gene: 140932 Rat Omim: 603291 Human SwissProt: Q12981 Human SwissProt: Q6QD59 Mouse SwissProt: Q8VHI8 Rat Unigene: 145726 Human Unigene: 21795 Mouse Unigene: 16757 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
圈套可能涉及靶向和融合高尔基体逆行运输囊泡与ER。维护ER网络所需。与抑制细胞死亡有关。
组织特异性：异构体1在心脏、脑、肝骨骼肌和胰腺中高表达。异构体3在胎盘、肺和肾中适度表达。异构体4在睾丸和小肠中高表达。