ABCB1 polyclonal antibody
产品名称： ABCB1 polyclonal antibody
英文名称： ABCB1 polyclonal antibody
产品编号： PAB16508
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of ABCB1.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to human ABCB1.
- Host:
- Rabbit
- Reactivity:
- Human
- Specificity:
- Cytoplasmic domain of human.
- Form:
- Liquid
- Purification:
- Immunoaffinity purification
- Concentration:
- 0.7 mg/mL
- Storage Buffer:
- In PBS (0.1% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -80°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (20 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Entrez GeneID:
- 5243
- Protein Accession#:
- P08183
- Gene Name:
- ABCB1
- Gene Alias:
- ABC20,CD243,CLCS,GP170,MDR1,MGC163296,P-GP,PGY1
- Gene Description:
- ATP-binding cassette, sub-family B (MDR/TAP), member 1
- Omim ID:
- 171050
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier. [provided by RefSeq
- Other Designations:
- ATP-binding cassette, subfamily B, member 1,P glycoprotein 1,P-glycoprotein 1,colchicin sensitivity,doxorubicin resistance,multidrug resistance 1,multidrug resistance protein 1
- Gene Pathway
- Related Disease
- Acquired Immunodeficiency Syndrome
- Acute Disease
- Addison Disease
- Adenocarcinoma
- Adenoma
- Alcoholism
- Alzheimer Disease
- Alzheimer disease
- Amnesia
- Anemia
- Arthritis, Rheumatoid
- Asthma
- Asthma
- Atherosclerosis
- Attention Deficit Disorder with Hyperactivity
- Bipolar Disorder
- Birth Weight
- Body Weight
- Brain Neoplasms